MASP1

gene product
CRARF, MASP, PRSS5
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
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228 antibodies from 25 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
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R&D Systems
3 antibodies
LifeSpan BioSciences, Inc.
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4 antibodies
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antibodies-online
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NovoPro Bioscience Inc.
1 antibody
Biorbyt
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Aviva Systems Biology
4 antibodies
Proteintech Group
1 antibody
Creative Biolabs
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OriGene
5 antibodies
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2 antibodies
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1 antibody
Atlas Antibodies
1 antibody
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3 antibodies
Invitrogen Antibodies
3 antibodies
St John's Laboratory
2 antibodies
MyBioSource
5 antibodies
Sigma-Aldrich
2 antibodies
Creative Diagnostics
2 antibodies
United States Biological
27 antibodies
Abbexa
3 antibodies
ProSci
1 antibody