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MSX2
gene productCRS2, FPP, HOX8, MSH, PFM, PFM1
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008]
Featured antibodies
 GeneTex |
 GTX129870 |
0 references | Polyclonal |
WB
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 Atlas Antibodies |
HPA005652 |
3 references | Polyclonal |
WB
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