Tissue expression
Cell line expression
ARHGEF12
gene productKIAA0382, LARG
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Featured antibodies
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0 references | Polyclonal |
ICC
IHC |
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0 references | Polyclonal |
WB
EL |