Tissue expression
Cell line expression
Protein structure
DNAJC2
DnaJ heat shock protein family (Hsp40) member C2MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 11971-1-AP | 2 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 11971-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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Novus Biologicals | NBP1-82627 | 3 references | Polyclonal |
WB
ICC
IHC
|
|
Atlas Antibodies | HPA020454 | Polyclonal |
WB
ICC
IHC
|
||
Biorbyt | orb2212669 | Polyclonal |
WB
ICC
IP
IHC |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider