GGTLC1

This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2008]

Description

Gamma-glutamyltransferase light chain 1

Tissue specificity

Group enriched (lung, testis)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins

Chromosome

20 (23985050 - 23988779)

Ensembl ID

ENSG00000149435  (ver. 103.38)

Orthologs

-

UniProt

Q9BX51

neXtProt

NX_Q9BX51

Human splice variants

Protein structure