Tissue expression
Cell line expression
Protein structure
AGTR1
Angiotensin II receptor type 1AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2020]
Top validated antibodies |
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Invitrogen Antibodies | PA5-20812 | 6 references | Polyclonal |
WB
ICC
IHC
OA |
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Proteintech Group | 25343-1-AP | 27 references | Polyclonal |
WB
EL
IHC
|
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Novus Biologicals | NBP1-77078 | 7 references | Polyclonal |
WB
ICC
IHC
|
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antibodies-online | ABIN1742173 | Polyclonal |
WB
ICC
IHC
FC |
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Abgent | AP10119b | Polyclonal |
WB
ICC
IHC
FC |
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