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DPYSL2
Dihydropyrimidinase like 2CRMP2, DHPRP2, DRP-2, DRP2
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Top validated antibodies |
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| LSBio |  LS-C198892 |
Polyclonal |
WB
EL
ICC
IHC
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| Proteintech Group | 14521-1-AP |
1 references | Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | 14686-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| Novus Biologicals | NBP1-50580 |
2 references | Monoclonal |
WB
IHC
PLA
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| NovoPro Bioscience Inc. | 109571 |
Polyclonal |
WB
EL
ICC
IP
IHC
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