DNASE1

gene product
DNL1
This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
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249 antibodies from 29 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
2 antibodies
Atlas Antibodies
1 antibody
Biorbyt
20 antibodies
Novus Biologicals
3 antibodies
Invitrogen Antibodies
4 antibodies
antibodies-online
84 antibodies
Signalway Antibody LLC
2 antibodies
LifeSpan BioSciences, Inc.
63 antibodies
Bioworld Technology, Inc
1 antibody
Enzo Life Sciences
1 antibody
OriGene
4 antibodies
Aviva Systems Biology
2 antibodies
Acris Antibodies GmbH
2 antibodies
St John's Laboratory
2 antibodies
Creative Biolabs
7 antibodies
Abnova Corporation
3 antibodies
Arigo
1 antibody
MyBioSource
4 antibodies
Boster Biological Technology
1 antibody
RabMAbs
1 antibody
United States Biological
14 antibodies
Creative Diagnostics
2 antibodies
Sigma-Aldrich
2 antibodies
ProSci
1 antibody
RayBiotech, Inc.
1 antibody
GenWay
5 antibodies
Abbexa
3 antibodies
EMD Millipore
1 antibody