Tissue expression
Cell line expression
Protein structure
CDH17
Cadherin 17cadherin, HPT-1
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Top validated antibodies |
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NSJ Bioreagents | ![]() |
Monoclonal |
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Proteintech Group | ![]() |
5 references | Polyclonal |
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Novus Biologicals | ![]() |
3 references | Monoclonal |
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Abnova Corporation | ![]() |
2 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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