Tissue expression
Cell line expression
Protein structure

BIN1

Bridging integrator 1
AMPH2, AMPHL, SH3P9 
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Mar 2016]
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522 antibodies from 42 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Invitrogen Antibodies
37 antibodies
Atlas Antibodies
2 antibodies
NSJ Bioreagents
3 antibodies
antibodies-online
137 antibodies
Novus Biologicals
29 antibodies
Biorbyt
84 antibodies
GeneTex
5 antibodies
OriGene
9 antibodies
FineTest Biotech
1 antibody
NovoPro Bioscience Inc.
1 antibody
Boster Biological Technology
4 antibodies
St John's Laboratory
4 antibodies
Bioworld Technology, Inc
1 antibody
Cusabio Biotech Co., Ltd
6 antibodies
Bethyl Laboratories
2 antibodies
HUABIO Research
1 antibody
Abnova Corporation
9 antibodies
Rockland Immunochemicals, Inc.
8 antibodies
Aviva Systems Biology
4 antibodies
Abgent
6 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
BioLegend
2 antibodies
Everest Biotech
1 antibody
Cell Signaling Technology, Inc
2 antibodies
ProSci
2 antibodies
MilliporeSigma / Merck KGaA
7 antibodies
Antibodies.com
1 antibody
Acris Antibodies GmbH
6 antibodies
Creative Biolabs
22 antibodies
Creative Diagnostics
8 antibodies
EMD Millipore
3 antibodies
MyBioSource
10 antibodies
Abbexa
12 antibodies
Abbiotec
1 antibody
Arigo
1 antibody
United States Biological
79 antibodies
Bioss
1 antibody
RabMAbs
1 antibody
RayBiotech, Inc.
2 antibodies
Leading Biology
4 antibodies
BioLegend (formerly Covance Antibody Products)
1 antibody