Tissue expression
Cell line expression
Protein structure
FZD8
Frizzled class receptor 8This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals | 2 references | Polyclonal |
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| Everest Biotech | Polyclonal |
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| Antibodies.com | Polyclonal |
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| antibodies-online | 2 references | Polyclonal |
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| LSBio | Polyclonal |
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