BDKRB2

This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008]

Description

bradykinin receptor B2

Protein family

FDA approved drug targets, G-protein coupled receptors, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

14:q32.2 (96204679 - 96244166)

Ensembl ID

ENSG00000168398  (ver. 99.38)

Orthologs

Mouse Bdkrb2: ENSMUSG00000021070

UniProt

P30411

neXtProt

NX_P30411

Human splice variants
Mouse splice variants