RAD50

gene product
hRad50, RAD50-2
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder. [provided by RefSeq, Apr 2010]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
429 antibodies from 28 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
8 antibodies
Novus Biologicals
29 antibodies
antibodies-online
150 antibodies
LifeSpan BioSciences, Inc.
90 antibodies
Invitrogen Antibodies
7 antibodies
Biorbyt
21 antibodies
Affinity Biosciences
2 antibodies
Bethyl Laboratories
3 antibodies
Abnova Corporation
4 antibodies
OriGene
7 antibodies
R&D Systems
2 antibodies
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
2 antibodies
St John's Laboratory
3 antibodies
Boster Biological Technology
2 antibodies
Aviva Systems Biology
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Acris Antibodies GmbH
1 antibody
MyBioSource
9 antibodies
Creative Biolabs
16 antibodies
Creative Diagnostics
7 antibodies
Cell Signaling Technology, Inc
2 antibodies
GenWay
5 antibodies
RabMAbs
2 antibodies
United States Biological
47 antibodies
EMD Millipore
2 antibodies
ProSci
1 antibody
Sigma-Aldrich
1 antibody