RAD50

gene product
hRad50, RAD50-2
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder. [provided by RefSeq, Apr 2010]
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GeneTex
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antibodies-online
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Atlas Antibodies
1 antibody
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Bioss
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Boster Biological Technology
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Aviva Systems Biology
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Acris Antibodies GmbH
1 antibody
MyBioSource
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Creative Biolabs
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Abbexa
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Creative Diagnostics
7 antibodies
Cell Signaling Technology, Inc
2 antibodies
GenWay
5 antibodies
RabMAbs
2 antibodies
United States Biological
47 antibodies
EMD Millipore
2 antibodies
ProSci
1 antibody
Sigma-Aldrich
1 antibody
CPTAC
2 antibodies