PPM1K

This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, Sep 2012]

Description

protein phosphatase, Mg2+/Mn2+ dependent 1K

Protein family

Disease related genes, Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Potential drug targets, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

4:q22.1 (88257620 - 88284769)

Ensembl ID

ENSG00000163644  (ver. 99.38)

Orthologs

Mouse Ppm1k: ENSMUSG00000037826

UniProt

Q8N3J5

neXtProt

NX_Q8N3J5

Human splice variants
Mouse splice variants