Tissue expression
Cell line expression
Protein structure
ABCA1
ATP binding cassette subfamily A member 1ABC1, HDLDT1, TGD
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019]
Top validated antibodies |
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Novus Biologicals | NB400-105 | 334 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
BN
GS
ChIP
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Invitrogen Antibodies | PA1-16789 | 8 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
BN
GS
ChIP
OA |
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GeneTex | GTX27360 | 1 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
GS
ChIP |
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antibodies-online | ABIN189744 | 259 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
GS
ChIP |
|
LSBio | LS-C153710 | Polyclonal |
WB
EL
ICC
IHC |
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider