Tissue expression
Cell line expression

AKAP13

gene product
AKAP-Lbc, ARHGEF13, BRX, c-lbc, HA-3, Ht31, LBC, PROTO-LB 
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012]
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202 antibodies from 28 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
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GeneTex
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Abgent
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NovoPro Bioscience Inc.
2 antibodies
Invitrogen Antibodies
12 antibodies
Cusabio Biotech Co., Ltd
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Aviva Systems Biology
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OriGene
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Acris Antibodies GmbH
2 antibodies
Atlas Antibodies
1 antibody
Boster Biological Technology
1 antibody
Bethyl Laboratories
2 antibodies
Bioworld Technology, Inc
1 antibody
Proteintech Group
1 antibody
MilliporeSigma / Merck KGaA
3 antibodies
NSJ Bioreagents
1 antibody
MyBioSource
3 antibodies
Abbexa
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
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Leading Biology
3 antibodies
Creative Diagnostics
1 antibody
Creative Biolabs
6 antibodies