TNFSF8

gene product
CD153, CD30LG
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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R&D Systems
17 antibodies
Novus Biologicals
58 antibodies
GeneTex
5 antibodies
OriGene
2 antibodies
Boster Biological Technology
2 antibodies
Affinity Biosciences
1 antibody
Proteintech Group
1 antibody
antibodies-online
100 antibodies
LifeSpan BioSciences, Inc.
91 antibodies
NSJ Bioreagents
1 antibody
Bioworld Technology, Inc
1 antibody
Invitrogen Antibodies
6 antibodies
Acris Antibodies GmbH
12 antibodies
Creative Biolabs
79 antibodies
Biorbyt
7 antibodies
Aviva Systems Biology
2 antibodies
Abnova Corporation
15 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Miltenyi Biotec
13 antibodies
Absolute Antibody
6 antibodies
St John's Laboratory
3 antibodies
EMD Millipore
1 antibody
United States Biological
14 antibodies
Creative Diagnostics
8 antibodies
MyBioSource
5 antibodies
GenWay
3 antibodies
Sigma-Aldrich
2 antibodies
Leading Biology
1 antibody