EIF4G2

gene product
DAP5, NAT1, p97
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
426 antibodies from 37 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
27 antibodies
Invitrogen Antibodies
9 antibodies
antibodies-online
136 antibodies
Proteintech Group
2 antibodies
OriGene
10 antibodies
Affinity Biosciences
3 antibodies
Biorbyt
22 antibodies
GeneTex
4 antibodies
Atlas Antibodies
2 antibodies
Aviva Systems Biology
4 antibodies
Cell Signaling Technology, Inc
3 antibodies
Abnova Corporation
6 antibodies
LifeSpan BioSciences, Inc.
55 antibodies
Bioworld Technology, Inc
1 antibody
NovoPro Bioscience Inc.
1 antibody
Acris Antibodies GmbH
4 antibodies
Arigo
2 antibodies
Santa Cruz Biotechnology
1 antibody
Signalway Antibody LLC
1 antibody
Bethyl Laboratories
3 antibodies
St John's Laboratory
3 antibodies
Abgent
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Boster Biological Technology
1 antibody
Creative Biolabs
14 antibodies
ProSci
5 antibodies
RabMAbs
2 antibodies
United States Biological
44 antibodies
MyBioSource
8 antibodies
Creative Diagnostics
5 antibodies
Active Motif
1 antibody
Leading Biology
5 antibodies
Sigma-Aldrich
5 antibodies
RayBiotech, Inc.
2 antibodies
GenWay
2 antibodies
EMD Millipore
1 antibody