CHST4

This gene encodes an N-acetylglucosamine 6-O sulfotransferase. The encoded enzyme transfers sulfate from 3'phosphoadenosine 5'phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins. This protein is localized to the Golgi and is involved in the modification of glycan structures on ligands of the lymphocyte homing receptor L-selectin. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]

Description

Carbohydrate sulfotransferase 4

Tissue specificity

Tissue enriched (gallbladder)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

16 (71525233 - 71538748)

Ensembl ID

ENSG00000140835  (ver. 103.38)

Orthologs

Mouse Chst4: ENSMUSG00000035930

UniProt

Q8NCG5

neXtProt

NX_Q8NCG5

Human splice variants
Mouse splice variants

Protein structure