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Protein structure
AK2
Adenylate kinase 2Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2. [provided by RefSeq, Nov 2010]
Top validated antibodies |
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| Proteintech Group |  11014-1-AP |
9 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 11014-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| LSBio | LS-C375168 |
Polyclonal |
WB
EL
IHC
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| NovoPro Bioscience Inc. | 107105 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| FineTest Biotech | FNab00245 |
Monoclonal |
WB
EL
ICC
IHC
FC
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