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Cell line expression
Protein structure
BAG3
BAG cochaperone 3BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  10599-1-AP |
110 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Enzo Life Sciences | ALX-803-323-C100 |
8 references | Monoclonal |
WB
EL
ICC
IP
IHC
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| Novus Biologicals | NBP2-27398 |
7 references | Polyclonal |
WB
ICC
IP
IHC
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| Invitrogen Antibodies | 10599-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| LSBio | LS-C148218 |
Polyclonal |
WB
IP
IHC
|
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