RET

gene product
CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008]
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Antibodies

 

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Antibodypedia Validation Initiative

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Conjugate

  or   Clear
Enhanced validation
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Validated within AVI
Eligible for validation within AVI
1078 antibodies from 37 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
50 antibodies
Cell Signaling Technology, Inc
7 antibodies
OriGene
36 antibodies
Abnova Corporation
16 antibodies
Santa Cruz Biotechnology
1 antibody
antibodies-online
457 antibodies
R&D Systems
18 antibodies
Boster Biological Technology
1 antibody
Biorbyt
66 antibodies
Aviva Systems Biology
12 antibodies
Abgent
11 antibodies
NovoPro Bioscience Inc.
7 antibodies
GeneTex
12 antibodies
Invitrogen Antibodies
17 antibodies
NSJ Bioreagents
2 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
127 antibodies
Acris Antibodies GmbH
16 antibodies