Tissue expression
Cell line expression

NLRP2

gene product
CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2 
This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
More gene data

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310 antibodies from 38 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
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Novus Biologicals
9 antibodies
antibodies-online
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NovoPro Bioscience Inc.
1 antibody
Invitrogen Antibodies
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Cusabio Biotech Co., Ltd
3 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
GeneTex
3 antibodies
Acris Antibodies GmbH
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Atlas Antibodies
2 antibodies
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13 antibodies
OriGene
5 antibodies
BioLegend
1 antibody
Boster Biological Technology
1 antibody
Antibodies.com
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Everest Biotech
2 antibodies
NSJ Bioreagents
2 antibodies
ABEOMICS Inc.
4 antibodies
Abgent
4 antibodies
Aviva Systems Biology
2 antibodies
R&D Systems
2 antibodies
Arigo
1 antibody
ProSci
3 antibodies
United States Biological
48 antibodies
RabMAbs
1 antibody
MyBioSource
5 antibodies
Leading Biology
4 antibodies
Creative Diagnostics
6 antibodies
Abbexa
6 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Abbiotec
1 antibody
RayBiotech, Inc.
1 antibody
Creative Biolabs
4 antibodies
GenWay
1 antibody
Rockland Immunochemicals, Inc.
1 antibody