NLRP2

gene product
CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2
This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
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307 antibodies from 36 providers.

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Antibody
Proteintech Group
1 antibody
Novus Biologicals
9 antibodies
antibodies-online
105 antibodies
Abnova Corporation
10 antibodies
NovoPro Bioscience Inc.
1 antibody
LifeSpan BioSciences, Inc.
34 antibodies
Invitrogen Antibodies
7 antibodies
GeneTex
3 antibodies
Acris Antibodies GmbH
9 antibodies
Atlas Antibodies
2 antibodies
Biorbyt
13 antibodies
OriGene
5 antibodies
BioLegend
1 antibody
Antibodies.com
2 antibodies
St John's Laboratory
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Everest Biotech
2 antibodies
NSJ Bioreagents
2 antibodies
ABEOMICS Inc.
4 antibodies
Abgent
4 antibodies
Aviva Systems Biology
2 antibodies
R&D Systems
2 antibodies
Arigo
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
ProSci
3 antibodies
United States Biological
48 antibodies
RabMAbs
1 antibody
MyBioSource
5 antibodies
Creative Diagnostics
6 antibodies
Creative Biolabs
4 antibodies
Leading Biology
4 antibodies
Abbexa
6 antibodies
Sigma-Aldrich
2 antibodies
Abbiotec
1 antibody
RayBiotech, Inc.
1 antibody
GenWay
1 antibody