Tissue expression
Cell line expression
Protein structure
PDE1A
Phosphodiesterase 1ACyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]). [supplied by OMIM, Oct 2009]
Top validated antibodies |
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| Proteintech Group | 5 references | Polyclonal |
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| LSBio | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Antibodies.com | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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