ADAM30

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is testis-specific and contains a polymorphic region, resulting in isoforms with varying numbers of C-terminal repeats. [provided by RefSeq, Jul 2008]

Description

ADAM metallopeptidase domain 30

Tissue specificity

Tissue enriched (testis)

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted membrane proteins
Protein evidence (Kim et al 2014)

Chromosome

1 (119893533 - 119896515)

Ensembl ID

ENSG00000134249  (ver. 103.38)

Orthologs

Mouse Adam30: ENSMUSG00000043468

UniProt

Q9UKF2

neXtProt

NX_Q9UKF2

Human splice variants
Mouse splice variants

Protein structure