DMPK

gene product
DM, DM1, DM1PK, DMK, MDPK, MT-PK
The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
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AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
2 antibodies
antibodies-online
103 antibodies
Novus Biologicals
7 antibodies
Invitrogen Antibodies
4 antibodies
Abnova Corporation
7 antibodies
GeneTex
2 antibodies
Aviva Systems Biology
3 antibodies
OriGene
4 antibodies
LifeSpan BioSciences, Inc.
50 antibodies
Boster Biological Technology
2 antibodies
Affinity Biosciences
1 antibody
NovoPro Bioscience Inc.
1 antibody
Biorbyt
7 antibodies
Acris Antibodies GmbH
3 antibodies
Creative Biolabs
5 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Abgent
1 antibody
R&D Systems
1 antibody
RabMAbs
1 antibody
St John's Laboratory
2 antibodies
Bioworld Technology, Inc
1 antibody
Sigma-Aldrich
4 antibodies
Creative Diagnostics
3 antibodies
United States Biological
26 antibodies
EMD Millipore
1 antibody
MyBioSource
1 antibody