KHK

This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Description

ketohexokinase

Protein family

Disease related genes, Enzymes, Mapped to UniProt SWISS-PROT, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

2:p23.3 (27086747 - 27100772)

Ensembl ID

ENSG00000138030  (ver. 84.38)

Orthologs

Mouse Khk: ENSMUSG00000029162

UniProt

P50053

neXtProt

NX_P50053

Human splice variants
Mouse splice variants