MLKL

gene product
FLJ34389
This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015]
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316 antibodies from 34 providers.

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Antibody
Novus Biologicals
28 antibodies
GeneTex
5 antibodies
Affinity Biosciences
5 antibodies
Abnova Corporation
5 antibodies
Biorbyt
32 antibodies
LifeSpan BioSciences, Inc.
53 antibodies
NovoPro Bioscience Inc.
3 antibodies
antibodies-online
88 antibodies
Cell Signaling Technology, Inc
7 antibodies
Boster Biological Technology
3 antibodies
St John's Laboratory
5 antibodies
Proteintech Group
1 antibody
Creative Diagnostics
6 antibodies
Aviva Systems Biology
2 antibodies
Acris Antibodies GmbH
2 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
Invitrogen Antibodies
4 antibodies
Arigo
1 antibody
Bioss
1 antibody
NSJ Bioreagents
1 antibody
OriGene
1 antibody
R&D Systems
1 antibody
RabMAbs
1 antibody
Creative Biolabs
15 antibodies
BioLegend
2 antibodies
ProSci
2 antibodies
Abiocode, Inc.
1 antibody
RayBiotech, Inc.
1 antibody
United States Biological
26 antibodies
MyBioSource
3 antibodies
Sigma-Aldrich
2 antibodies
Abbexa
3 antibodies
Abgent
1 antibody
EMD Millipore
1 antibody