CYB5R3

gene product
DIA1
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Validated by best practice
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
242 antibodies from 27 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
Proteintech Group
2 antibodies
OriGene
5 antibodies
Novus Biologicals
8 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
7 antibodies
antibodies-online
81 antibodies
Abnova Corporation
9 antibodies
GeneTex
4 antibodies
LifeSpan BioSciences, Inc.
26 antibodies
Acris Antibodies GmbH
9 antibodies
Biorbyt
15 antibodies
NSJ Bioreagents
3 antibodies
Aviva Systems Biology
3 antibodies
Invitrogen Antibodies
2 antibodies
Arigo
4 antibodies
Abgent
2 antibodies
Bioworld Technology, Inc
1 antibody
Everest Biotech
1 antibody
MyBioSource
9 antibodies
RabMAbs
4 antibodies
St John's Laboratory
2 antibodies
Creative Biolabs
3 antibodies
Creative Diagnostics
3 antibodies
United States Biological
24 antibodies
Sigma-Aldrich
1 antibody
GenWay
1 antibody