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Protein structure
CYB5R3
Cytochrome b5 reductase 3DIA1
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
Top validated antibodies |
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| Proteintech Group |  10894-1-AP |
Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 10894-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| OriGene | TA501385 |
Monoclonal |
WB
ICC
IHC
FC
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| NovoPro Bioscience Inc. | 109657 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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| FineTest Biotech | FNab02116 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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