Tissue expression
Cell line expression
Protein structure
ERLIN1
ER lipid raft associated 1C10orf69, Erlin-1, KE04, SPFH1, SPG62
The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016]
Top validated antibodies |
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Proteintech Group | ![]() |
6 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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FineTest Biotech | ![]() |
Polyclonal |
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