Tissue expression
Cell line expression

PYGL

gene product
GSD6 
This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2011]
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316 antibodies from 30 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
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Atlas Antibodies
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
Novus Biologicals
5 antibodies
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2 antibodies
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21 antibodies
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8 antibodies
antibodies-online
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LifeSpan BioSciences, Inc.
82 antibodies
Invitrogen Antibodies
18 antibodies
GeneTex
2 antibodies
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7 antibodies
OriGene
3 antibodies
Bioworld Technology, Inc
1 antibody
MilliporeSigma / Merck KGaA
3 antibodies
Affinity Biosciences
1 antibody
Bethyl Laboratories
1 antibody
Boster Biological Technology
1 antibody
Acris Antibodies GmbH
1 antibody
Abbexa
10 antibodies
MyBioSource
5 antibodies
Aviva Systems Biology
2 antibodies
ProSci
1 antibody
United States Biological
14 antibodies
Leading Biology
2 antibodies
Creative Diagnostics
3 antibodies
RayBiotech, Inc.
2 antibodies
Exalpha Biologicals, Inc.
1 antibody
Creative Biolabs
1 antibody