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NEDD4
NEDD4 E3 ubiquitin protein ligaseKIAA0093, MGC176705, NEDD4-1, RPF1
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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| Proteintech Group |  21698-1-AP |
17 references | Polyclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN953640 |
4 references | Polyclonal |
WB
IHC
FC
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| Invitrogen Antibodies | PA5-17463 |
1 references | Polyclonal |
WB
ICC
OA
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| Biorbyt | orb1097977 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| NovoPro Bioscience Inc. | 113096 |
Polyclonal |
WB
EL
IP
IHC
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