Tissue expression
Cell line expression
Protein structure
NECTIN3
Nectin cell adhesion molecule 3CD113, CDw113, DKFZP566B0846, nectin-3, PPR3, PVRL3, PVRR3
This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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| Proteintech Group | 5 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Novus Biologicals | 2 references | Polyclonal |
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| OriGene | Monoclonal |
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| NSJ Bioreagents | Polyclonal |
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