DDC

Dopa decarboxylase

AADC

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]

Ensembl	UniProt	RefSeq	Entrez
ENST00000357936 ENSP00000350616	P20711.199 P20711 A0A0S2Z3N4	NP_000781.2 NP_000781	DDC 1644
ENST00000380984 ENSP00000370371	P20711.199 P20711	NP_001229819.2 NP_001229819	DDC 1644
ENST00000420203 ENSP00000408626	C9JMP0		DDC 1644
ENST00000426377 ENSP00000395069	P20711.199 P20711	NP_001229817.2 NP_001229817	DDC 1644
ENST00000430300 ENSP00000389422	H7BZF7		DDC 1644
ENST00000431062 ENSP00000399184	P20711.199 P20711		DDC 1644
ENST00000444124 ENSP00000403644	P20711.199 P20711 A0A0S2Z3N4	NP_001076440.2 NP_001076440	DDC 1644
ENST00000615193 ENSP00000484104	P20711.199 P20711	NP_001229818.1 NP_001229818	DDC 1644
ENST00000617822 ENSP00000478385	A0A087WU57	NP_001229816.1 NP_001229816	DDC 1644
ENST00000622873 ENSP00000479110	A0A087WV24	NP_001229815.1 NP_001229815	DDC 1644

Ensembl	UniProt	RefSeq	Entrez
ENSMUST00000066237 ENSMUSP00000068525	O88533.163 O88533 Q5SUV8		Ddc 13195
ENSMUST00000109659 ENSMUSP00000105286	O88533.163 O88533 Q5SUV8	NP_057881.1 NP_057881	Ddc 13195
ENSMUST00000155690 ENSMUSP00000121096	Q5SUV9		Ddc 13195
ENSMUST00000178704 ENSMUSP00000136467	O88533.163 O88533 Q5SUV8	NP_001177377.1 NP_001177377	Ddc 13195

More gene data

Top validated antibodies
Proteintech Group	10166-1-AP	10 references	Polyclonal	WB EL IP IHC
Invitrogen Antibodies	PA5-25450	1 references	Polyclonal	WB ICC IHC FC
antibodies-online	ABIN2840377	1 references	Polyclonal	WB ICC IHC FC
Abgent	AP5536a		Polyclonal	WB ICC IHC FC
NSJ Bioreagents	F54418		Polyclonal	WB ICC IHC FC

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566 antibodies from 47 providers.

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	Antibody	Refs	Type
Invitrogen Antibodies 19 antibodies
	PA5-25450	1	Polyclonal
	10166-1-AP		Polyclonal

Proteintech Group 1 antibody
	10166-1-AP	10	Polyclonal

antibodies-online 155 antibodies
	ABIN2840377	1	Polyclonal
	ABIN651727		Polyclonal

GeneTex 7 antibodies
	GTX30448	10	Polyclonal
	GTX31550		Polyclonal

NSJ Bioreagents 3 antibodies
	F54418		Polyclonal
	F54418-0.08ML		Polyclonal

Atlas Antibodies 2 antibodies
	HPA017742		Polyclonal
	AMAb91089		Monoclonal

Abgent 7 antibodies
	AP5536a		Polyclonal
	APS11687		Polyclonal

NovoPro Bioscience Inc. 11 antibodies
	121321		Polyclonal
	110059		Polyclonal

R&D Systems 4 antibodies
	AF3564		Polyclonal
	MAB3564		Monoclonal

Novus Biologicals 15 antibodies
	AF3564		Polyclonal
	NB300-252	1	Polyclonal

Aviva Systems Biology 6 antibodies
	OAAB02950		Polyclonal
	ARP41425_T100		Polyclonal

Boster Biological Technology 1 antibody
	A01374		Polyclonal

Biorbyt 48 antibodies
	orb1239897		Polyclonal
	orb1930458		Polyclonal

LSBio 110 antibodies
	LS-B10123		Polyclonal
	LS-C197031		Monoclonal

OriGene 6 antibodies
	TA326643		Polyclonal
	MO15100-100		Monoclonal

FineTest Biotech 1 antibody
	FNab02510		Polyclonal

Abnova Corporation 8 antibodies
	PAB9598	3	Polyclonal
	H00001644-M18		Monoclonal

Cusabio Biotech Co., Ltd 5 antibodies
	CSB-PA006583LA01HU		Polyclonal
	CSB-PA006583GA01HU		Polyclonal

ProSci 4 antibodies
	7447		Polyclonal
	29-571		Polyclonal

Acris Antibodies GmbH 7 antibodies
	AP08633PU-N	1	Polyclonal
	AP08632PU-N		Polyclonal

St John's Laboratory 4 antibodies
	STJ70697		Polyclonal
	STJ23355		Polyclonal

Everest Biotech 1 antibody
	EB06740		Polyclonal

BioLegend 2 antibodies
	869501		Monoclonal
	869502		Monoclonal

Bioss 16 antibodies
	bs-0180R		Polyclonal
	bsm-54061R		Monoclonal

Abbkine Scientific Co.Ltd. 1 antibody
	ABP58339		Polyclonal

Affinity Biosciences 1 antibody
	DF12386		Polyclonal

Antibodies.com 1 antibody
	A83188		Polyclonal

Cell Signaling Technology, Inc 1 antibody
	13561		Monoclonal

HUABIO Research 1 antibody
	ET1704-94		Monoclonal

MyBioSource 4 antibodies
	MBS9201818		Polyclonal
	MBS129595		Polyclonal

United States Biological 38 antibodies
	034530		Polyclonal
	034530-AP		Polyclonal

Arigo 3 antibodies
	ARG52258		Polyclonal
	ARG52260		Polyclonal

Leading Biology 7 antibodies
	APR07526G		Polyclonal
	APR07513G		Polyclonal

MilliporeSigma / Merck KGaA 7 antibodies
	D0180		Monoclonal
	HPA017742		Polyclonal

Sino Biological Inc. 6 antibodies
	10560-R005		Monoclonal
	10560-MM04		Monoclonal

Creative Biolabs 21 antibodies
	MOB-2355z		Monoclonal
	MOB-2355z-F(E)		Monoclonal

PhosphoSolutions 3 antibodies
	417-DDC		Polyclonal
	418-DDCH		Polyclonal

Abbexa 9 antibodies
	abx128444		Polyclonal
	abx302246		Polyclonal

Abbiotec 2 antibodies
	250623		Polyclonal
	253132		Polyclonal

RayBiotech, Inc. 3 antibodies
	101-10384		Monoclonal
	119-16631		Polyclonal

Creative Diagnostics 3 antibodies
	DCABH-11238		Monoclonal
	DPABH-09406		Monoclonal

EMD Millipore 3 antibodies
	AB1569		Polyclonal
	AB119		Polyclonal

Enzo Life Sciences 2 antibodies
	BML-AZ1030-0050		Polyclonal
	BML-SA487-0100		Polyclonal

GenWay 3 antibodies
	18-003-43698		Polyclonal
	18-662-20032		Polyclonal

BioLegend (formerly Covance Antibody Products) 1 antibody
	PRB-323P		Polyclonal

RabMAbs 1 antibody
	ab131282		Monoclonal

Rockland Immunochemicals, Inc. 2 antibodies
	600-401-AU2		Polyclonal
	600-401-X02		Polyclonal

DDC

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