Tissue expression
Cell line expression
Protein structure
PRC1
Protein regulator of cytokinesis 1ASE1
This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Top validated antibodies |
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Proteintech Group | 15617-1-AP | 10 references | Polyclonal |
WB
EL
ICC
IP
IHC
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Invitrogen Antibodies | 15617-1-AP | Polyclonal |
WB
ICC
IHC
OA |
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Atlas Antibodies | HPA034521 | Polyclonal |
WB
ICC
IHC
|
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NovoPro Bioscience Inc. | 114169 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
GeneTex | GTX31478 | Polyclonal |
WB
EL
ICC
IHC |
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