Tissue expression
Cell line expression
Protein structure
CELSR2
Cadherin EGF LAG seven-pass G-type receptor 2ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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R&D Systems | ![]() |
1 references | Polyclonal |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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