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BPGM
Bisphosphoglycerate mutase2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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| Atlas Antibodies |  HPA016493 |
1 references | Polyclonal |
WB
IHC
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| LSBio | LS-B10833 |
Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | 17173-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| Novus Biologicals | NBP2-59493-100ul |
Monoclonal |
WB
EL
ICC
FC
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| Proteintech Group | 17173-1-AP |
Polyclonal |
WB
EL
IP
IHC
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