EPHB2

gene product
DRT, EPHT3, ERK, Hek5, Tyro5
This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
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R&D Systems
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Invitrogen Antibodies
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Abbkine Scientific Co.Ltd.
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Everest Biotech
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SignalChem
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RayBiotech, Inc.
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Arigo
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Leading Biology
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Creative Diagnostics
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Sino Biological Inc.
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Abbiotec
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EMD Millipore
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MilliporeSigma / Merck KGaA
3 antibodies