ADCY10

The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014]

Description

adenylate cyclase 10

Protein family

Disease related genes, Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

1:q24.2 (167809386 - 167914215)

Ensembl ID

ENSG00000143199  (ver. 99.38)

Orthologs

Mouse Adcy10: ENSMUSG00000026567

UniProt

Q96PN6

neXtProt

NX_Q96PN6

Human splice variants
Mouse splice variants