Tissue expression
Cell line expression

PC

gene product
PCB 
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
More gene data

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389 antibodies from 37 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
2 antibodies
Atlas Antibodies
2 antibodies
Invitrogen Antibodies
13 antibodies
Novus Biologicals
25 antibodies
GeneTex
6 antibodies
NovoPro Bioscience Inc.
5 antibodies
OriGene
8 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
LifeSpan BioSciences, Inc.
64 antibodies
antibodies-online
98 antibodies
St John's Laboratory
4 antibodies
Cusabio Biotech Co., Ltd
9 antibodies
Affinity Biosciences
1 antibody
Biorbyt
19 antibodies
Aviva Systems Biology
4 antibodies
Acris Antibodies GmbH
3 antibodies
Antibodies.com
1 antibody
NSJ Bioreagents
1 antibody
Arigo
2 antibodies
Abgent
3 antibodies
Abnova Corporation
2 antibodies
Bioworld Technology, Inc
1 antibody
Boster Biological Technology
1 antibody
ProSci
2 antibodies
Creative Diagnostics
2 antibodies
Everest Biotech
1 antibody
RabMAbs
4 antibodies
Abbexa
12 antibodies
MyBioSource
6 antibodies
Creative Biolabs
23 antibodies
EMD Millipore
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
RayBiotech, Inc.
1 antibody
United States Biological
37 antibodies
Leading Biology
4 antibodies
MilliporeSigma / Merck KGaA
4 antibodies