CCND3

gene product
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
756 antibodies from 39 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
6 antibodies
antibodies-online
252 antibodies
GeneTex
4 antibodies
Novus Biologicals
6 antibodies
LifeSpan BioSciences, Inc.
147 antibodies
OriGene
13 antibodies
Acris Antibodies GmbH
8 antibodies
Affinity Biosciences
4 antibodies
Boster Biological Technology
4 antibodies
Abnova Corporation
8 antibodies
Cell Signaling Technology, Inc
2 antibodies
Aviva Systems Biology
6 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Arigo
2 antibodies
NovoPro Bioscience Inc.
5 antibodies
Proteintech Group
2 antibodies
Biorbyt
47 antibodies
NSJ Bioreagents
3 antibodies
R&D Systems
1 antibody
Bioworld Technology, Inc
4 antibodies
Creative Biolabs
32 antibodies
Abgent
6 antibodies
St John's Laboratory
6 antibodies
ProSci
1 antibody
Creative Diagnostics
15 antibodies
MyBioSource
19 antibodies
RabMAbs
3 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
BioLegend
3 antibodies
Atlas Antibodies
1 antibody
Signalway Antibody LLC
1 antibody
United States Biological
105 antibodies
Enzo Life Sciences
2 antibodies
Sigma-Aldrich
3 antibodies
Abbiotec
1 antibody
Exalpha Biologicals, Inc.
1 antibody
GenWay
4 antibodies
BioLegend (formerly Covance Antibody Products)
1 antibody