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Cell line expression
Protein structure
XPA
XPA, DNA damage recognition and repair factorXP1, XPAC
This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]
Top validated antibodies |
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| GeneTex |  GTX103168 |
2 references | Polyclonal |
WB
ICC
IP
IHC
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| Invitrogen Antibodies | MA5-13835 |
16 references | Monoclonal |
WB
ICC
IHC
OA
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| Proteintech Group | 16462-1-AP |
6 references | Polyclonal |
WB
EL
ICC
IP
|
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| antibodies-online | ABIN2842484 |
1 references | Polyclonal |
WB
IHC
FC
|
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| LSBio | LS-C198443 |
Monoclonal |
WB
EL
ICC
|
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