STAT5B

gene product
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
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531 antibodies from 34 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
26 antibodies
Invitrogen Antibodies
9 antibodies
R&D Systems
4 antibodies
Proteintech Group
2 antibodies
antibodies-online
168 antibodies
Abnova Corporation
16 antibodies
Acris Antibodies GmbH
12 antibodies
LifeSpan BioSciences, Inc.
68 antibodies
NovoPro Bioscience Inc.
13 antibodies
Bethyl Laboratories, Inc.
3 antibodies
Abgent
12 antibodies
OriGene
10 antibodies
Santa Cruz Biotechnology
1 antibody
Bioworld Technology, Inc
2 antibodies
Aviva Systems Biology
8 antibodies
Biorbyt
19 antibodies
NSJ Bioreagents
2 antibodies
BosterBio
2 antibodies
Arigo
1 antibody
GeneTex
6 antibodies
RabMAbs
2 antibodies
BioLegend
4 antibodies
MyBioSource
10 antibodies
RayBiotech, Inc.
4 antibodies
United States Biological
81 antibodies
Creative Biolabs
3 antibodies
St John's Laboratory
2 antibodies
Abiocode, Inc.
1 antibody
EMD Millipore
6 antibodies
Creative Diagnostics
2 antibodies
Sigma-Aldrich
5 antibodies
GenWay
2 antibodies
Active Motif
1 antibody