Tissue expression
Cell line expression
Protein structure

STAT5B

Signal transducer and activator of transcription 5B
 
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
More gene data

All Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
936 antibodies from 43 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
68 antibodies
Proteintech Group
3 antibodies
R&D Systems
10 antibodies
Novus Biologicals
22 antibodies
antibodies-online
314 antibodies
Abnova Corporation
17 antibodies
OriGene
20 antibodies
Acris Antibodies GmbH
12 antibodies
NovoPro Bioscience Inc.
13 antibodies
Cusabio Biotech Co., Ltd
11 antibodies
GeneTex
5 antibodies
FineTest Biotech
2 antibodies
St John's Laboratory
9 antibodies
Boster Biological Technology
4 antibodies
Abgent
12 antibodies
Bethyl Laboratories
2 antibodies
HUABIO Research
1 antibody
NSJ Bioreagents
4 antibodies
Bioworld Technology, Inc
2 antibodies
Santa Cruz Biotechnology
1 antibody
Affinity Biosciences
3 antibodies
Aviva Systems Biology
8 antibodies
Aladdin Scientific Corporation
1 antibody
Arigo
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
Cell Signaling Technology, Inc
1 antibody
ProSci
8 antibodies
Creative Biolabs
55 antibodies
RabMAbs
2 antibodies
BioLegend
4 antibodies
MyBioSource
10 antibodies
RayBiotech, Inc.
4 antibodies
Abbexa
17 antibodies
United States Biological
81 antibodies
Leading Biology
11 antibodies
Abiocode, Inc.
1 antibody
Creative Diagnostics
4 antibodies
EMD Millipore
6 antibodies
MilliporeSigma / Merck KGaA
5 antibodies
GenWay
2 antibodies
Active Motif
1 antibody