CDC27

gene product
ANAPC3, APC3, D0S1430E, D17S978E, NUC2
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC), which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate, which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats, which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 22 and Y. [provided by RefSeq, May 2014]
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Proteintech Group
2 antibodies
GeneTex
6 antibodies
NSJ Bioreagents
1 antibody
Boster Biological Technology
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antibodies-online
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Invitrogen Antibodies
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Rockland Immunochemicals, Inc.
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Bioworld Technology, Inc
1 antibody
St John's Laboratory
3 antibodies
Abgent
4 antibodies
Bethyl Laboratories
2 antibodies
Cell Signaling Technology, Inc
1 antibody
ProSci
1 antibody
MyBioSource
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Creative Diagnostics
3 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Abbexa
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GenWay
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18 antibodies
Abbiotec
2 antibodies
RayBiotech, Inc.
2 antibodies
HUABIO Research
1 antibody
United States Biological
17 antibodies
Leading Biology
3 antibodies
EMD Millipore
1 antibody
RabMAbs
1 antibody