Tissue expression
Cell line expression
Protein structure

UMOD

Uromodulin
 
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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622 antibodies from 38 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
15 antibodies
Proteintech Group
1 antibody
Abnova Corporation
11 antibodies
antibodies-online
183 antibodies
Invitrogen Antibodies
12 antibodies
Biorbyt
77 antibodies
NSJ Bioreagents
3 antibodies
R&D Systems
6 antibodies
OriGene
11 antibodies
Boster Biological Technology
2 antibodies
Atlas Antibodies
2 antibodies
FineTest Biotech
1 antibody
NovoPro Bioscience Inc.
1 antibody
Everest Biotech
2 antibodies
Affinity Biosciences
1 antibody
Aviva Systems Biology
4 antibodies
Santa Cruz Biotechnology
1 antibody
Bioworld Technology, Inc
2 antibodies
Antibodies.com
2 antibodies
Cusabio Biotech Co., Ltd
2 antibodies
St John's Laboratory
4 antibodies
ProSci
5 antibodies
Acris Antibodies GmbH
6 antibodies
GeneTex
4 antibodies
Abgent
4 antibodies
MyBioSource
9 antibodies
MilliporeSigma / Merck KGaA
5 antibodies
Creative Diagnostics
7 antibodies
Creative Biolabs
19 antibodies
Abbexa
6 antibodies
RayBiotech, Inc.
3 antibodies
United States Biological
76 antibodies
Leading Biology
5 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
EMD Millipore
1 antibody
GenWay
1 antibody