MYLK

gene product
MLCK, MLCK1, MYLK1, smMLCK
This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
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319 antibodies from 32 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
7 antibodies
Proteintech Group
1 antibody
Abnova Corporation
7 antibodies
Boster Biological Technology
2 antibodies
Atlas Antibodies
1 antibody
antibodies-online
123 antibodies
NovoPro Bioscience Inc.
3 antibodies
NSJ Bioreagents
4 antibodies
Biorbyt
20 antibodies
Abgent
3 antibodies
Acris Antibodies GmbH
3 antibodies
OriGene
4 antibodies
LifeSpan BioSciences, Inc.
54 antibodies
Invitrogen Antibodies
4 antibodies
GeneTex
3 antibodies
Affinity Biosciences
4 antibodies
FabGennix
3 antibodies
RabMAbs
2 antibodies
St John's Laboratory
6 antibodies
ProSci
2 antibodies
Antibodies.com
1 antibody
Aviva Systems Biology
3 antibodies
Everest Biotech
1 antibody
MyBioSource
9 antibodies
Bioworld Technology, Inc
1 antibody
Santa Cruz Biotechnology
1 antibody
Abbkine Scientific Co.Ltd.
4 antibodies
United States Biological
25 antibodies
Abbexa
3 antibodies
Sigma-Aldrich
2 antibodies
Creative Diagnostics
1 antibody