TRIM28

The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]

Description

tripartite motif containing 28

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

19:q13.43 (58544064 - 58550722)

Ensembl ID

ENSG00000130726  (ver. 99.38)

Orthologs

Mouse Trim28: ENSMUSG00000005566

UniProt

Q13263

neXtProt

NX_Q13263

Human splice variants
Mouse splice variants