TTK

gene product
CT96, MPH1, MPS1, MPS1L1
This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
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Antibodies

 

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Conjugate

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Eligible for validation within AVI
460 antibodies from 31 providers.

Antibody properties

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Antibody
Proteintech Group
1 antibody
Novus Biologicals
9 antibodies
GeneTex
3 antibodies
Santa Cruz Biotechnology
1 antibody
Invitrogen Antibodies
10 antibodies
Abnova Corporation
10 antibodies
antibodies-online
149 antibodies
LifeSpan BioSciences, Inc.
110 antibodies
NovoPro Bioscience Inc.
1 antibody
Affinity Biosciences
4 antibodies
Biorbyt
19 antibodies
Aviva Systems Biology
3 antibodies
OriGene
11 antibodies
Abgent
3 antibodies
R&D Systems
2 antibodies
Acris Antibodies GmbH
2 antibodies
Bioworld Technology, Inc
1 antibody
Cell Signaling Technology, Inc
2 antibodies
Creative Diagnostics
7 antibodies
Bethyl Laboratories
2 antibodies
Boster Biological Technology
1 antibody
Creative Biolabs
17 antibodies
MyBioSource
7 antibodies
St John's Laboratory
3 antibodies
Abbexa
14 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
United States Biological
45 antibodies
Sigma-Aldrich
3 antibodies
EMD Millipore
2 antibodies
Leading Biology
1 antibody