LAMA1

This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]

Description

laminin subunit alpha 1

Protein family

Disease related genes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Protein evidence (Peptideatlas)

Chromosome

18:p11.31 (6941742 - 7117797)

Ensembl ID

ENSG00000101680  (ver. 98.38)

Orthologs

Mouse Lama1: ENSMUSG00000032796

UniProt

P25391

neXtProt

NX_P25391

Human splice variants
Mouse splice variants