PRKACB

The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2014]

Description

protein kinase, cAMP-dependent, beta catalytic subunit

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014), RAS pathway related proteins

Chromosome

1:p31.1 (84078062 - 84238498)

Ensembl ID

ENSG00000142875  (ver. 84.38)

Orthologs

Mouse Prkacb: ENSMUSG00000005034

UniProt

P22694

neXtProt

NX_P22694

Human splice variants
Mouse splice variants